In his lecture, Prof. Gonzalo de Prat Gay explored the role of biomolecular condensation in viral replication and its implications for p53-related cancer. He discussed how proteins like phosphoprotein (P) facilitate phase separation within viral factories, crucial for gene transcription and replication. Prof. Gonzalo also revealed a novel interaction between the human papillomavirus (HPV) and p53, shedding light on potential therapeutic avenues. Furthermore, his research highlighted the broader significance of biomolecular condensation in cancer biology, offering insights into p53 mutation and aggregation. Overall, his work not only deepens our understanding of condensation mechanisms but also holds promise for future drug discovery and treatment strategies.
